Ｐｅｒｍｅａｔｉｏｎ

"When was the real voice of Western Medicine in Japan first heard? On the occasion of arrival of Catholic missionaries supported by Portuguese voyagers on mid-16th century?
In the age of Nanban (Iberian) and K?m? (People of Northern Europe) medicine in the first quarter of the 17th century? Or on the lifting of the ban on the study of Rangaku (Dutch studies) by the Sh?gun Yoshimune on the mid-18th century? Its growth was influenced often, widely and greatly by pressure from various sources, both within Japan, and countries in Europe or even the US, which had no formal relations with Japan at that time.
The author in fully convinced that the growth of Western medicine in Japan was the seeds bed, or at least cultural crucible of the modern history of our country itself."